![]() It is this property that enables the virus to invade CD4 + T cells (and certain other cells that express CD4). ![]() Infection of a host cell requires that the cell have a surface protein that can serve as a receptor for the envelope protein of the retrovirus. Thus it is able to make genetic information flow in the reverse (RNA ->DNA) of its normal direction Reverse transcriptase is a DNA polymerase that uses RNA as its template. molecules of the enzyme reverse transcriptase.many copies of an envelope protein embedded in the lipid bilayer of its envelope.an outer envelope which was derived from the plasma membrane of its host.Could immunosuppressed patients be at risk from the retroviruses present in the transplanted cells? The probability that the original hosts for HIV-1 and HIV-2 were some other primate suggests that retroviruses can move from one species to another.Ī typical, "minimal" retrovirus consists of: Transplant recipients must have their immune systems suppressed if the transplant is to avoid rejection. This is troublesome because of the efforts that are being made to transplant pig tissue into humans (e.g., fetal pig cells into the brains of patients with Parkinson's disease). In February 1997 it was reported that pig cells contain a retrovirus capable of infecting human cells (at least, in vitro). HIV-1 and HIV-2, the agents that cause AIDS, are retroviruses. ![]() The genome of retroviruses consists of RNA not DNA. ![]()
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